Traverse the Spider-Verse with a swarm of Spiders familiar, fresh and flabbergasting! As the vicious Morlun targets wall-crawlers across all realities, Spider-Man Noir returns, Gwen Stacy is Earth-65's Spider-Woman and Peni Parker dons the sensational mech-suit known as SP//dr! When the end of the Spider-Verse looms, Spider-Ham and Arana head into action, the legacy of Spider-UK passes to a new champion, Sergei Kravinoff becomes the Hunter-Spider...

When an immitation Joker begins distributing a derivitive of Joker Juice and inciting riots in Gotham, a bogus Batman incites the citizens to immitate Batman, become vigilantes, and take out the "Jokerz." The result is weeks of chaos in Gotham, with the police and Batman standing helplessly by as Gotham's citizens maim and kill each other.